杰弗里·K. 甘特图,Ph值.D.
Professor of Biology, College of 艺术与科学, School of Biological 科学s
Co-Director, Histology and Imaging Core
位置
凭证
教育
Post-Doctoral Training
研究
目前的研究
Dr. 甘特图's laboratory is investigating the mechanisms of nociception using the powerful genetic toolkit of the fruit fly 果蝇 melanogaster. Pain affects all of our lives in some way, yet we know only a little of how pain works and how to block it. The tiny fly might be able to lead us to the next generation of improved medications for pain in humans.
Selected publications
Hale C*, Moulton J, Otis Y* and 甘特图G. Armadillo regulates nociceptive sensitivity in the absence of injury. 摩尔的痛苦. 2022 Apr;18 PMID: 35712882
McParland A*, Moulton J*, Brann C*, Hale C*, Otis Y*, 甘特图G. The Brinker repressor system regulates injury-induced nociceptive sensitization in 果蝇 melanogaster. 摩尔的痛苦. 2021 Jan-Dec;17:17448069211037401.
Brann CL*, Moulton JK*, 甘特图g·. Glypicans Dally and Dally-like control injury-induced allodynia in 果蝇. 摩尔的痛苦. 2019 Jan-Dec; 15. PMID: 31132919.
Gjelsvik KJ*, Follansbee TL*, and 甘特图g·. Bone Morphogenetic Protein Glass Bottom Boat (BMP5/6/7/8) and its receptor Wishful Thinking (BMPRII) are required for injury-induced allodynia in 果蝇. 摩尔的痛苦. 2018 Jan-Dec; 14.
Follansbee TL*, Gjelsvik KJ*, Brann CL*, McParland AL*, Longhurst CA*, Galko乔丹, 甘特图g·. Nociceptive Sensitization Requires BMP Signaling via the Canonical SMAD Pathway. J >. 2017 Aug 30;37(35):8524-8533
McParland AL*, Follansbee TL*, Vesenka GD, Panaitiu AE *, 甘特图g·. Steroid receptor isoform expression in 果蝇 nociceptor neurons is required for normal dendritic arbor and sensitivity. 《正规澳门赌场网络》. 2015 Oct 23;10(10):e0140785
McParland AL*, Follansbee TL*, 甘特图g·. Measurement of larval activity in the 果蝇 活动监视器. J Vis Exp. 2015 Apr 30;(98):e52684
甘特图g·, Desilets JB, Davis-Knowlton JA, Panaitiu AE *, Sweezy米, Sungail J, 谭禄*, 亚当斯是*, 费舍尔EA *, O ' brien JRM *, 金凯公里*, 海因里希·R. 果蝇 female precopulatory behavior is modulated by ecdysteroids (2012) Journal of Insect Physiology, 58 (3): 413-419
甘特图g·, Panaitiu AE *, Desilets JB *, Davis-Heim JA, 费舍尔EA *, 谭禄*, 海因里希·R, 布坎南EB *, 布鲁克斯公里*, 肯尼太*, 佛得角毫克*, 唐尼J *, 亚当斯是*, Grenier JS *, Maddula *, 沙阿P *, 金凯公里*, O ' brien JRM.* 果蝇 male courtship behavior is modulated by ecdysteroids (2011) Journal of Insect Physiology, 57 (9): 1179-1184
甘特图g·, Walton KL*, Merriman JO*, Salmon MV*, 布鲁克斯公里*, Maddula *, Kravitz EA. Increased male-male courtship in ecdysone receptor deficient adult flies (2007) Behavior Genetics, 37 (3): 507-512. (接受ed 12/27/2006, published 1/20/07)
* indicates student co-author
资助基金
1 r15ns131952-01 08/01/2023 - 07/31/2026 Investigation of Armadillo/ß-catenin Mechanisms Influencing Nociceptive Sensitivity in 果蝇
研究兴趣
Neurobiology of nociception.